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Insulin efsitora alfa
CAS No. 2131038-11-2
Insulin efsitora alfa ( —— )
产品货号. M36800 CAS No. 2131038-11-2
Insulin efsitora alfa (LY-3209590) 是一种胰岛素受体 (insulin receptor，IR) 的选择性激动剂。Insulin efsitora alfa 是一种融合蛋白，由与人免疫球蛋白 G2 (IgG2) 片段可结晶 (Fc) 结构域融合人胰岛素受体 (IR) 激动剂组成，分子量为 64.1 kDa。Insulin efsitora alfa 耐受性良好，在糖尿病中有潜在的应用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥5530 | 有现货 |
|
| 5MG | ￥9044 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Insulin efsitora alfa
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Insulin efsitora alfa (LY-3209590) 是一种胰岛素受体 (insulin receptor，IR) 的选择性激动剂。Insulin efsitora alfa 是一种融合蛋白，由与人免疫球蛋白 G2 (IgG2) 片段可结晶 (Fc) 结构域融合人胰岛素受体 (IR) 激动剂组成，分子量为 64.1 kDa。Insulin efsitora alfa 耐受性良好，在糖尿病中有潜在的应用。
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产品描述Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes.
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体外实验——
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体内实验——
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同义词——
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通路Angiogenesis
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靶点IGF-1R
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受体IGF-1R
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研究领域——
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适应症——
化学信息
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CAS Number2131038-11-2
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分子量
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分子式——
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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NVP-AEW541
NVP-AEW541 (AEW-541, AEW541) 是一种有效的选择性 IGF-1R 抑制剂，IC50 为 86 nM。
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IGF-I 24-41
IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).
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KW-2450 free base
KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
